Biomarker Discovery
Biomarker Discovery
Biomarkers, such as proteins, are naturally occurring biomolecules useful for measuring the prognosis and/or progress of diseases and therapies. They are normally present in small amounts in blood or tissue. When the amounts of these molecules change, they may indicate disease. Poochon developed a reliable platform, PROMICMAPPER, and a novel proteomic pathway analysis tool, PROMICPATH, for quantitative global protein profiling and proteomic pathway analysis, which is an ideal combination to differentiate diseased and normal samples for biomarker discovery.
+ P701: Biomarker Screening
Identification of Differentially Expressed Proteins From Two Groups of Samples
Service Description
• Identification of differentially expressed proteins from two groups of samples (e.g., healthy and diseased)
• Workflow: Sample preparation, LC-MS/MS analysis, data analysis, and results report
Deliverables
• Protein Biomarker Profiling Report
• List of identified proteins with relative abundance
• List of all identified proteins with matched peptides sequences
• List of protein biomarker candidates that are differentially expressed among samples (e.g., > 2 folds)
• Data normalization, statistical analysis, volcano plots, heat maps
• Data figures
Suitable Sample Type
• Frozen cell pellets, tissues, or serum/plasma samples
• Identification of differentially expressed proteins from two groups of samples (e.g., healthy and diseased)
• Workflow: Sample preparation, LC-MS/MS analysis, data analysis, and results report
• Protein Biomarker Profiling Report
• List of identified proteins with relative abundance
• List of all identified proteins with matched peptides sequences
• List of protein biomarker candidates that are differentially expressed among samples (e.g., > 2 folds)
• Data normalization, statistical analysis, volcano plots, heat maps
• Data figures
• Frozen cell pellets, tissues, or serum/plasma samples
submission Guidelines
